ben mentioned to me about 2 weeks ago that when installing update rollups for exchange 2007 you should start with the CAS servers first. i found an MS article that said the same thing.

so i installed the latest rollup on the CAS, hub transport, and then finally the mailbox servers. i ran the updates from an administrator-level command line. the updates don’t really apply in a few minutes. i think in just about every instance the update took from 10-15 minutes to apply per server (at least). i rebooted the servers after applying the update, however, i believe the only servers that actually prompted me for a reboot were the mailbox servers.

source:
http://technet.microsoft.com/en-us/library/ee221147(EXCHG.80).aspx

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